Kami menyampaikan klaim mengenai penganiayaan yang meluas terhadap tahanan Palestina kepada pihak berwenang yang terlibat.

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5-fold bigger action than did the WT (determine 3a). Immunoblotting verified the expression levels of mutant Aph1 and PS1 have been comparable to stages while in the WT. These results propose that γ-secretase with these two Aph1 mutations exhibit Increased protease activity for application.

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Laporan B'tselem yang bertajuk Welcome to Hell, memuat kesaksian dari 55 tahanan Palestina yang baru saja dibebaskan. Mereka menggambarkan memburuknya kondisi di dalam penjara secara dramatis sejak dimulainya pertikaian di Gaza sejak 10 bulan lalu.

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the gap concerning the oxygen atom of Thr164 of Aph1 and the oxygen atom of Tyr466 of PS1 is predicted to become 3.5 Å, suggesting that a hydrogen bond (H...O length, about one.eight Å) is shaped in these side chains (Figure 7b). The T164A mutation may perhaps reduce the hydrogen bond with PS1 Y466, resulting in versatile movement in the carboxy terminus of PS1. We propose that Aph1 mutations control protease exercise through conformational modifications in PS1.

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